Injuries are an inherent part of the game of football, and the San Francisco 49ers are feeling the effects as they prepare ...

The 49ers have listed George Kittle as doubtful to play this Sunday against the Los Angeles Rams. That means backup tight end ...

Running back Isaac Guerendo is fast. And he's big. But the San Francisco 49ers rookie is a work in progress. His lone carry ...

Earlier this week, 49ers head coach Kyle Shanahan said he doesn't ask Brock Purdy to do too much on the field. That was an ...

The last time the Los Angeles Rams and San Francisco 49ers met, head coaches Sean McVay and Kyle Shanahan were without some ...

The San Francisco 49ers head to Southern California to take on the division-rival Los Angeles Rams on Sunday. They do so with ...

There may not be two teams more injured than the Los Angeles Rams and San Francisco 49ers, which will have a big impact on ...

Also likely to be out is tight end George Kittle, who is doubtful and battling a hamstring issue. That will further ding the ...

The recent retirement of Aaron Donald, the three-time Defensive Player of the Year and a key figure in the Rams' defense, has ...

Suddenly in doubt for the Week 3 game at L.A. are tight end George Kittle, defensive end Nick Bosa, and cornerback Charvarius ...

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Head coach Kyle Shanahan shared the final injury report ahead of the 49ers Week 3 matchup and discussed the team's ...